该研究提出了一种能够利用AAV递送较大基因载荷的策略，从而为之前认为无法进行AAV基因治疗的疾病提供了治疗可能性。 治疗性基因的递送对于基因治疗至关重要。腺相关病毒（AAV）因其优越的基因分割灵活性和强大的基因重建效率，成为携带基因载荷的主要载体 ...

New research sheds light on how cells repair damaged DNA. For the first time, the team has mapped the activity of repair proteins in individual human cells. The study demonstrates how these proteins ...

Intratumoral Ral-binding protein 1 (RalBP1) expression as a potential predictor of bevacizumab treatment efficacy in patients with ovarian cancer. This is an ASCO Meeting Abstract from the 2024 ASCO ...

Astrocytes shed their supportive role and unlock hidden neurogenic potential, offering new hope for brain injury recovery through cutting-edge epigenetic reprogramming. Study: DNA methylation controls ...

Unquestionably, we will emerge from this revolutionary period with modified views of components of cells and how they operate, but only, however, to await the emergence of the next revolutionary phase ...

Elegen has launched ENFINIA™ IVT Ready DNA, a cell-free gene synthesis platform that provides full-length linear DNA templates encoded poly(A) tails for in vitro transcription. The templates are ...

Franklin W. Stahl, an American molecular biologist whose landmark 1957-58 experiment with colleague Matthew Meselson revealed how DNA replicates, helping pave the way for a revolution in genetics ...